Angioendotheliomatosis is a rare, benign condition with polymorphic clinical manifestations ranging from macules to plaques or nodules that may be purpuric, ulcerated or scleroderma-like [1-7]. It is often associated with systemic diseases [8]. Some cases have been descibed in patients with cryoproteinaemia [7]. One hypothesis to explain the association with these diseases is that they are all characterised by high oxidative stress, which is also increased by haemodialysis and facilitates vascular [7]. Furthermore, in these diseases, hypoxia and skin reperfusion processes can occur which locally increase the concentration of oxygen free radicals, which are known to be a potent angiogenic factor [1, 2]. It is characterised by a specific histological pattern of proliferating dermal capillaries, the lumens of which are obliterated by proliferating endothelial cells [9-11]. Two anatomopathological types are frequently found. These are intravascular reactive angioendotheliomatosis and diffuse reactive angioendotheliomatosis [2]. The second form, which is the one described in our clinical case, may be an accompanied by cavernous dilatations, intravascular thrombi and, in some cases, epithelioid endothelium. Endothelial atypia is an unusual phenomenon althrougt it is found in some patients. This atypia was not found in our case [2].

The differential diagnosis is most often made with kaposi’s sarcoma [6, 9]. It is a benign pathology [8, 11]. The diagnosis is anatomopathological [7]. The treatment is not well codified. It is based on the management of risk factors for atheroma and on clean surgery. The efficacy of systematic corticosteroid therapy, effective anticoagulant and revascularisation have been reported [12].